Cas 9

Récepteur de la Testostérone

Séquence nucléique

Chaîne de référence
1       10        20        30        40        50        60        70        80        90
ATGGAAGTGCAGTTAGGGCTGGGAAGGGTCTACCCTCGGCCGCCGTCCAAGACCTACCGAGGAGCTTTCCAGAATCTGTTCCAGAGCGTG
CGCGAAGTGATCCAGAACCCGGGCCCCAGGCACCCAGAGGCCGCGAGCGCAGCACCTCCCGGCGCCAGTTTGCTGCTGCTGCAGCAGCAG
CAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAAGAGACTAGCCCCAGGCAGCAGCAGCAGCAGCAGGGT
GAGGATGGTTCTCCCCAAGCCCATCGTAGAGGCCCCACAGGCTACCTGGTCCTGGATGAGGAACAGCAACCTTCACAGCCGCAGTCGGCC
CTGGAGTGCCACCCCGAGAGAGGTTGCGTCCCAGAGCCTGGAGCCGCCGTGGCCGCCAGCAAGGGGCTGCCGCAGCAGCTGCCAGCACCT
CCGGACGAGGATGACTCAGCTGCCCCATCCACGTTGTCCCTGCTGGGCCCCACTTTCCCCGGCTTAAGCAGCTGCTCCGCTGACCTTAAA
GACATCCTGAGCGAGGCCAGCACCATGCAACTCCTTCAGCAACAGCAGCAGGAAGCAGTATCCGAAGGCAGCAGCAGCGGGAGAGCGAGG
GAGGCCTCGGGGGCTCCCACTTCCTCCAAGGACAATTACTTAGGGGGCACTTCGACCATTTCTGACAACGCCAAGGAGTTGTGTAAGGCA
GTGTCGGTGTCCATGGGCCTGGGTGTGGAGGCGTTGGAGCATCTGAGTCCAGGGGAACAGCTTCGGGGGGATTGCATGTACGCCCCACTT
TTGGGAGTTCCACCCGCTGTGCGTCCCACTCCTTGTGCCCCATTGGCCGAATGCAAAGGTTCTCTGCTAGACGACAGCGCAGGCAAGAGC
ACTGAAGATACTGCTGAGTATTCCCCTTTCAAGGGAGGTTACACCAAAGGGCTAGAAGGCGAGAGCCTAGGCTGCTCTGGCAGCGCTGCA
GCAGGGAGCTCCGGGACACTTGAACTGCCGTCTACCCTGTCTCTCTACAAGTCCGGAGCACTGGACGAGGCAGCTGCGTACCAGAGTCGC
GACTACTACAACTTTCCACTGGCTCTGGCCGGACCGCCGCCCCCTCCGCCGCCTCCCCATCCCCACGCTCGCATCAAGCTGGAGAACCCG
CTGGACTACGGCAGCGCCTGGGCGGCTGCGGCGGCGCAGTGCCGCTATGGGGACCTGGCGAGCCTGCATGGCGCGGGTGCAGCGGGACCC
GGTTCTGGGTCACCCTCAGCCGCCGCTTCCTCATCCTGGCACACTCTCTTCACAGCCGAAGAAGGCCAGTTGTATGGACCGTGTGGTGGT
GGTGGGGGTGGTGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGAGGCGGGAGCTGTAGCCCCCTAC
GGCTACACTCGGCCCCCTCAGGGGCTGGCGGGCCAGGAAAGCGACTTCACCGCACCTGATGTGTGGTACCCTGGCGGCATGGTGAGCAGA
GTGCCCTATCCCAGTCCCACTTGTGTCAAAAGCGAAATGGGCCCCTGGATGGATAGCTACTCCGGACCTTACGGGGACATGCGTTTGGAG
ACTGCCAGGGACCATGTTTTGCCCATTGACTATTACTTTCCACCCCAGAAGACCTGCCTGATCTGTGGAGATGAAGCTTCTGGGTGTCAC
TATGGAGCTCTCACATGTGGAAGCTGCAAGGTCTTCTTCAAAAGAGCCGCTGAAGGGAAACAGAAGTACCTGTGCGCCAGCAGAAATGAT
TGCACTATTGATAAATTCCGAAGGAAAAATTGTCCATCTTGTCGTCTTCGGAAATGTTATGAAGCAGGGATGACTCTGGGAGCCCGGAAG
CTGAAGAAACTTGGTAATCTGAAACTACAGGAGGAAGGAGAGGCTTCCAGCACCACCAGCCCCACTGAGGAGACAACCCAGAAGCTGACA
GTGTCACACATTGAAGGCTATGAATGTCAGCCCATCTTTCTGAATGTCCTGGAAGCCATTGAGCCAGGTGTAGTGTGTGCTGGACACGAC
AACAACCAGCCCGACTCCTTTGCAGCCTTGCTCTCTAGCCTCAATGAACTGGGAGAGAGACAGCTTGTACACGTGGTCAAGTGGGCCAAG
GCCTTGCCTGGCTTCCGCAACTTACACGTGGACGACCAGATGGCTGTCATTCAGTACTCCTGGATGGGGCTCATGGTGTTTGCCATGGGC
TGGCGATCCTTCACCAATGTCAACTCCAGGATGCTCTACTTCGCCCCTGATCTGGTTTTCAATGAGTACCGCATGCACAAGTCCCGGATG
TACAGCCAGTGTGTCCGAATGAGGCACCTCTCTCAAGAGTTTGGATGGCTCCAAATCACCCCCCAGGAATTCCTGTGCATGAAAGCACTG
CTACTCTTCAGCATTATTCCAGTGGATGGGCTGAAAAATCAAAAATTCTTTGATGAACTTCGAATGAACTACATCAAGGAACTCGATCGT
ATCATTGCATGCAAAAGAAAAAATCCCACATCCTGCTCAAGACGCTTCTACCAGCTCACCAAGCTCCTGGACTCCGTGCAGCCTATTGCG
AGAGAGCTGCATCAGTTCACTTTTGACCTGCTAATCAAGTCACACATGGTGAGCGTGGACTTTCCGGAAATGATGGCAGAGATCATCTCT
GTGCAAGTGCCCAAGATCCTTTCTGGGAAAGTCAAGCCCATCTATTTCCACACCCAGTGA

Chaîne du sujet
1       10        20        30        40        50        60        70        80        90
ATGGAAGTGCAGTTAGGGCTGGGAAGGGTCTACCCTCGGCCGCCGTCCAAGACCTACCGAGGAGCTTTCCAGAATCTGTTCCAGAGCGTG
CGCGAAGTGATCCAGAACCCGGGCCCCAGGCACCCAGAGGCCGCGAGCGCAGCACCTCCCGGCGCCAGTTTGCTGCTGCTGCAGCAGCAG
CAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAGCAAGAGACTAGCCCCAGGCAGCAGCAGCAGCAGCAGGGT
GAGGATGGTTCTCCCCAAGCCCATCGTAGAGGCCCCACAGGCTACCTGGTCCTGGATGAGGAACAGCAACCTTCACAGCCGCAGTCGGCC
CTGGAGTGCCACCCCGAGAGAGGTTGCGTCCCAGAGCCTGGAGCCGCCGTGGCCGCCAGCAAGGGGCTGCCGCAGCAGCTGCCAGCACCT
CCGGACGAGGATGACTCAGCTGCCCCATCCACGTTGTCCCTGCTGGGCCCCACTTTCCCCGGCTTAAGCAGCTGCTCCGCTGACCTTAAA
GACATCCTGAGCGAGGCCAGCACCATGCAACTCCTTCAGCAACAGCAGCAGGAAGCAGTATCCGAAGGCAGCAGCAGCGGGAGAGCGAGG
GAGGCCTCGGGGGCTCCCACTTCCTCCAAGGACAATTACTTAGGGGGCACTTCGACCATTTCTGACAACGCCAAGGAGTTGTGTAAGGCA
GTGTCGGTGTCCATGGGCCTGGGTGTGGAGGCGTTGGAGCATCTGAGTCCAGGGGAACAGCTTCGGGGGGATTGCATGTACGCCCCACTT
TTGGGAGTTCCACCCGCTGTGCGTCCCACTCCTTGTGCCCCATTGGCCGAATGCAAAGGTTCTCTGCTAGACGACAGCGCAGGCAAGAGC
ACTGAAGATACTGCTGAGTATTCCCCTTTCAAGGGAGGTTACACCAAAGGGCTAGAAGGCGAGAGCCTAGGCTGCTCTGGCAGCGCTGCA
GCAGGGAGCTCCGGGACACTTGAACTGCCGTCTACCCTGTCTCTCTACAAGTCCGGAGCACTGGACGAGGCAGCTGCGTACCAGAGTCGC
GACTACTACAACTTTCCACTGGCTCTGGCCGGACCGCCGCCCCCTCCGCCGCCTCCCCATCCCCACGCTCGCATCAAGCTGGAGAACCCG
CTGGACTACGGCAGCGCCTGGGCGGCTGCGGCGGCGCAGTGCCGCTATGGGGACCTGGCGAGCCTGCATGGCGCGGGTGCAGCGGGACCC
GGTTCTGGGTCACCCTCAGCCGCCGCTTCCTCATCCTGGCACACTCTCTTCACAGCCGAAGAAGGCCAGTTGTATGGACCGTGTGGTGGT
GGTGGGGGTGGTGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGGCGAGGCGGGAGCTGTAGCCCCCTAC
GGCTACACTCGGCCCCCTCAGGGGCTGGCGGGCCAGGAAAGCGACTTCACCGCACCTGATGTGTGGTACCCTGGCGGCATGGTGAGCAGA
GTGCCCTATCCCAGTCCCACTTGTGTCAAAAGCGAAATGGGCCCCTGGATGGATAGCTACTCCGGACCTTACGGGGACATGCGTTTGGAG
ACTGCCAGGGACCATGTTTTGCCCATTGACTATTACTTTCCACCCCAGAAGACCTGCCTGATCTGTGGAGATGAAGCTTCTGGGTGTCAC
TATGGAGCTCTCACATGTGGAAGCTGCAAGGTCTTCTTCAAAAGAGCCGCTGAAGGGAAACAGAAGTACCTGTGCGCCAGCAGAAATGAT
TGCACTATTGATAAATTCCGAAGGAAAAATTGTCCATCTTGTCGTCTTCGGAAATGTTATGAAGCAGGGATGACTCTGGGAGCCCGGAAG
CTGAAGAAACTTGGTAATCTGAAACTACAGGAGGAAGGAGAGGCTTCCAGCACCACCAGCCCCACTGAGGAGACAACCCAGAAGCTGACA
GTGTCACACATTGAAGGCTATGAATGTCAGCCCATCTTTCTGAATGTCCTGGAAGCCATTGAGCCAGGTGTAGTGTGTGCTGGACACGAC
AACAACCAGCCCGACTCCTTTGCAGCCTTGCTCTCTAGCCTCAATGAACTGGGAGAGAGACAGCTTGTACACGTGGTCAAGTGGGCCAAG
GCCTTGCCTGGCTTCCGCAACTTACACGTGGACGACCAGATGGCTGTCATTCAGTACTCCTGGATGGGGCTCATGGTGTTTGCCATGGGC
TGGCGATCCTTCACCAATGTCAACTCCAGGATGCTCTACTTCGCCCCTGATCTGGTTTTCAATGAGTACTGCATGCACAAGTCCCGGATG
TACAGCCAGTGTGTCCGAATGAGGCACCTCTCTCAAGAGTTTGGATGGCTCCAAATCACCCCCCAGGAATTCCTGTGCATGAAAGCACTG
CTACTCTTCAGCATTATTCCAGTGGATGGGCTGAAAAATCAAAAATTCTTTGATGAACTTCGAATGAACTACATCAAGGAACTCGATCGT
ATCATTGCATGCAAAAGAAAAAATCCCACATCCTGCTCAAGACGCTTCTACCAGCTCACCAAGCTCCTGGACTCCGTGCAGCCTATTGCG
AGAGAGCTGCATCAGTTCACTTTTGACCTGCTAATCAAGTCACACATGGTGAGCGTGGACTTTCCGGAAATGATGGCAGAGATCATCTCT
GTGCAAGTGCCCAAGATCCTTTCTGGGAAAGTCAAGCCCATCTATTTCCACACCCAGTGA

Séquence protéique

Chaîne de référence
1                           10                            20                            30
MetGluValGlnLeuGlyLeuGlyArgValTyrProArgProProSerLysThrTyrArgGlyAlaPheGlnAsnLeuPheGlnSerVal
ArgGluValIleGlnAsnProGlyProArgHisProGluAlaAlaSerAlaAlaProProGlyAlaSerLeuLeuLeuLeuGlnGlnGln
GlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGluThrSerProArgGlnGlnGlnGlnGlnGlnGly
GluAspGlySerProGlnAlaHisArgArgGlyProThrGlyTyrLeuValLeuAspGluGluGlnGlnProSerGlnProGlnSerAla
LeuGluCysHisProGluArgGlyCysValProGluProGlyAlaAlaValAlaAlaSerLysGlyLeuProGlnGlnLeuProAlaPro
ProAspGluAspAspSerAlaAlaProSerThrLeuSerLeuLeuGlyProThrPheProGlyLeuSerSerCysSerAlaAspLeuLys
AspIleLeuSerGluAlaSerThrMetGlnLeuLeuGlnGlnGlnGlnGlnGluAlaValSerGluGlySerSerSerGlyArgAlaArg
GluAlaSerGlyAlaProThrSerSerLysAspAsnTyrLeuGlyGlyThrSerThrIleSerAspAsnAlaLysGluLeuCysLysAla
ValSerValSerMetGlyLeuGlyValGluAlaLeuGluHisLeuSerProGlyGluGlnLeuArgGlyAspCysMetTyrAlaProLeu
LeuGlyValProProAlaValArgProThrProCysAlaProLeuAlaGluCysLysGlySerLeuLeuAspAspSerAlaGlyLysSer
ThrGluAspThrAlaGluTyrSerProPheLysGlyGlyTyrThrLysGlyLeuGluGlyGluSerLeuGlyCysSerGlySerAlaAla
AlaGlySerSerGlyThrLeuGluLeuProSerThrLeuSerLeuTyrLysSerGlyAlaLeuAspGluAlaAlaAlaTyrGlnSerArg
AspTyrTyrAsnPheProLeuAlaLeuAlaGlyProProProProProProProProHisProHisAlaArgIleLysLeuGluAsnPro
LeuAspTyrGlySerAlaTrpAlaAlaAlaAlaAlaGlnCysArgTyrGlyAspLeuAlaSerLeuHisGlyAlaGlyAlaAlaGlyPro
GlySerGlySerProSerAlaAlaAlaSerSerSerTrpHisThrLeuPheThrAlaGluGluGlyGlnLeuTyrGlyProCysGlyGly
GlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGluAlaGlyAlaValAlaProTyr
GlyTyrThrArgProProGlnGlyLeuAlaGlyGlnGluSerAspPheThrAlaProAspValTrpTyrProGlyGlyMetValSerArg
ValProTyrProSerProThrCysValLysSerGluMetGlyProTrpMetAspSerTyrSerGlyProTyrGlyAspMetArgLeuGlu
ThrAlaArgAspHisValLeuProIleAspTyrTyrPheProProGlnLysThrCysLeuIleCysGlyAspGluAlaSerGlyCysHis
TyrGlyAlaLeuThrCysGlySerCysLysValPhePheLysArgAlaAlaGluGlyLysGlnLysTyrLeuCysAlaSerArgAsnAsp
CysThrIleAspLysPheArgArgLysAsnCysProSerCysArgLeuArgLysCysTyrGluAlaGlyMetThrLeuGlyAlaArgLys
LeuLysLysLeuGlyAsnLeuLysLeuGlnGluGluGlyGluAlaSerSerThrThrSerProThrGluGluThrThrGlnLysLeuThr
ValSerHisIleGluGlyTyrGluCysGlnProIlePheLeuAsnValLeuGluAlaIleGluProGlyValValCysAlaGlyHisAsp
AsnAsnGlnProAspSerPheAlaAlaLeuLeuSerSerLeuAsnGluLeuGlyGluArgGlnLeuValHisValValLysTrpAlaLys
AlaLeuProGlyPheArgAsnLeuHisValAspAspGlnMetAlaValIleGlnTyrSerTrpMetGlyLeuMetValPheAlaMetGly
TrpArgSerPheThrAsnValAsnSerArgMetLeuTyrPheAlaProAspLeuValPheAsnGluTyrArgMetHisLysSerArgMet
TyrSerGlnCysValArgMetArgHisLeuSerGlnGluPheGlyTrpLeuGlnIleThrProGlnGluPheLeuCysMetLysAlaLeu
LeuLeuPheSerIleIleProValAspGlyLeuLysAsnGlnLysPhePheAspGluLeuArgMetAsnTyrIleLysGluLeuAspArg
IleIleAlaCysLysArgLysAsnProThrSerCysSerArgArgPheTyrGlnLeuThrLysLeuLeuAspSerValGlnProIleAla
ArgGluLeuHisGlnPheThrPheAspLeuLeuIleLysSerHisMetValSerValAspPheProGluMetMetAlaGluIleIleSer
ValGlnValProLysIleLeuSerGlyLysValLysProIleTyrPheHisThrGln

Chaîne du sujet
1                           10                            20                            30
MetGluValGlnLeuGlyLeuGlyArgValTyrProArgProProSerLysThrTyrArgGlyAlaPheGlnAsnLeuPheGlnSerVal
ArgGluValIleGlnAsnProGlyProArgHisProGluAlaAlaSerAlaAlaProProGlyAlaSerLeuLeuLeuLeuGlnGlnGln
GlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGlnGluThrSerProArgGlnGlnGlnGlnGlnGlnGly
GluAspGlySerProGlnAlaHisArgArgGlyProThrGlyTyrLeuValLeuAspGluGluGlnGlnProSerGlnProGlnSerAla
LeuGluCysHisProGluArgGlyCysValProGluProGlyAlaAlaValAlaAlaSerLysGlyLeuProGlnGlnLeuProAlaPro
ProAspGluAspAspSerAlaAlaProSerThrLeuSerLeuLeuGlyProThrPheProGlyLeuSerSerCysSerAlaAspLeuLys
AspIleLeuSerGluAlaSerThrMetGlnLeuLeuGlnGlnGlnGlnGlnGluAlaValSerGluGlySerSerSerGlyArgAlaArg
GluAlaSerGlyAlaProThrSerSerLysAspAsnTyrLeuGlyGlyThrSerThrIleSerAspAsnAlaLysGluLeuCysLysAla
ValSerValSerMetGlyLeuGlyValGluAlaLeuGluHisLeuSerProGlyGluGlnLeuArgGlyAspCysMetTyrAlaProLeu
LeuGlyValProProAlaValArgProThrProCysAlaProLeuAlaGluCysLysGlySerLeuLeuAspAspSerAlaGlyLysSer
ThrGluAspThrAlaGluTyrSerProPheLysGlyGlyTyrThrLysGlyLeuGluGlyGluSerLeuGlyCysSerGlySerAlaAla
AlaGlySerSerGlyThrLeuGluLeuProSerThrLeuSerLeuTyrLysSerGlyAlaLeuAspGluAlaAlaAlaTyrGlnSerArg
AspTyrTyrAsnPheProLeuAlaLeuAlaGlyProProProProProProProProHisProHisAlaArgIleLysLeuGluAsnPro
LeuAspTyrGlySerAlaTrpAlaAlaAlaAlaAlaGlnCysArgTyrGlyAspLeuAlaSerLeuHisGlyAlaGlyAlaAlaGlyPro
GlySerGlySerProSerAlaAlaAlaSerSerSerTrpHisThrLeuPheThrAlaGluGluGlyGlnLeuTyrGlyProCysGlyGly
GlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGlyGluAlaGlyAlaValAlaProTyr
GlyTyrThrArgProProGlnGlyLeuAlaGlyGlnGluSerAspPheThrAlaProAspValTrpTyrProGlyGlyMetValSerArg
ValProTyrProSerProThrCysValLysSerGluMetGlyProTrpMetAspSerTyrSerGlyProTyrGlyAspMetArgLeuGlu
ThrAlaArgAspHisValLeuProIleAspTyrTyrPheProProGlnLysThrCysLeuIleCysGlyAspGluAlaSerGlyCysHis
TyrGlyAlaLeuThrCysGlySerCysLysValPhePheLysArgAlaAlaGluGlyLysGlnLysTyrLeuCysAlaSerArgAsnAsp
CysThrIleAspLysPheArgArgLysAsnCysProSerCysArgLeuArgLysCysTyrGluAlaGlyMetThrLeuGlyAlaArgLys
LeuLysLysLeuGlyAsnLeuLysLeuGlnGluGluGlyGluAlaSerSerThrThrSerProThrGluGluThrThrGlnLysLeuThr
ValSerHisIleGluGlyTyrGluCysGlnProIlePheLeuAsnValLeuGluAlaIleGluProGlyValValCysAlaGlyHisAsp
AsnAsnGlnProAspSerPheAlaAlaLeuLeuSerSerLeuAsnGluLeuGlyGluArgGlnLeuValHisValValLysTrpAlaLys
AlaLeuProGlyPheArgAsnLeuHisValAspAspGlnMetAlaValIleGlnTyrSerTrpMetGlyLeuMetValPheAlaMetGly
TrpArgSerPheThrAsnValAsnSerArgMetLeuTyrPheAlaProAspLeuValPheAsnGluTyrCysMetHisLysSerArgMet
TyrSerGlnCysValArgMetArgHisLeuSerGlnGluPheGlyTrpLeuGlnIleThrProGlnGluPheLeuCysMetLysAlaLeu
LeuLeuPheSerIleIleProValAspGlyLeuLysAsnGlnLysPhePheAspGluLeuArgMetAsnTyrIleLysGluLeuAspArg
IleIleAlaCysLysArgLysAsnProThrSerCysSerArgArgPheTyrGlnLeuThrLysLeuLeuAspSerValGlnProIleAla
ArgGluLeuHisGlnPheThrPheAspLeuLeuIleLysSerHisMetValSerValAspPheProGluMetMetAlaGluIleIleSer
ValGlnValProLysIleLeuSerGlyLysValLysProIleTyrPheHisThrGln

Structure 3D de la molécule

Propriétés de la molécule impliquée