RdRp
Par Naoum Salamé
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Dernière modification
16/02/2024 15:13
Sars-CoV-2 : RNA-dependent RNA polymerase
Extrait de l'article du New York Times
NSP11 et NSP12
/protein_id="YP_009725312.1"
/note="nsp12; NiRAN and RdRp;
protein_id="YP_009725307.1"
Extrait de PDB 6M71 SARS-Cov-2 RNA-dependent RNA polymerase in complex with cofactors
This protein assembles genetic letters into new virus genomes. Researchers have found that the antiviral remdesivir interferes with NSP12 in other coronaviruses, and trials are now underway to see if the drug can treat Covid-19.
Another sequence, NSP11, overlaps part of the same stretch of RNA. But it’s not clear if the tiny protein encoded by this gene has any function at all.