Figure1- Article Junwen Luan
Par Naoum Salamé
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Dernière modification
19/05/2020 16:10
Fig. 1. Alignment of RBM region of S proteins from SARS-CoV-2 and SARS-CoV. (A) Sequence alignment of RBM region of S protein from SARS-CoV-2 and SARS-CoV. ▲ represents the six key amino acids in the S protein interacting with human ACE2. For SARS-CoV, they are Y442, L472, N479, D480, T487 and Y491. The S protein sequence of SARS-CoV-2 comes from YP_009724390.1, and the S protein sequence of SARS-CoV comes from NP_828851.1. (B) Alignment of the structure of ACE2 recognition of RBD from SARS-CoV-2 and SARS-CoV. Human ACE2 (hACE2), SARS-CoV-2 RBD, and SARS-CoV RBD are in orange red, blue, and green, respectively. (For interpretation of the references to colour in this figure legend, the reader is referred to the Web version of this article.)